Number of amino acids: 145
Molecular weight: 15670.8
Theoretical pI: 11.41
Total number of negatively charged residues (Asp + Glu): 13
Total number of positively charged residues (Arg + Lys): 21
Atomic composition:
Carbon C 679
Hydrogen H 1131
Nitrogen N 221
Oxygen O 203
Sulfur S 1
Formula: C679H1131N221O203S1Total number of atoms: 2235
Extinction coefficients:
Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water.
Ext. coefficient 8480
Abs 0.1% (=1 g/l) 0.541, assuming ALL Cys residues appear as half cystines
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 71.68
This classifies the protein as unstable.
Aliphatic index: 92.97
Grand average of hydropathicity (GRAVY): -0.284
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Please note the modified algorithm for extinction coefficient.