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Persistence Targets lists


Rank: 1 Rv0885 SwissProt: P0A5D5 Q10546
Status: Expressed [edit]
Analysis of PDB     TmH1
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 2 Rv2780 aldSwissProt: P30234 O33322
Status: expressed [edit]
Analysis of PDBPhormidium lapideumTmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

KEGG Reductive carboxylate cycle (CO2 fixation) KEGG Nitrogen metabolism

Gateway Clones

Comments

 
Rank: 3 Rv3290c latSwissProt: P63509 P96895
Status: In PDB [edit]
Analysis of PDB2CIN 2CJD 2CJG 2CJHTmH     
Metabolism Related Targetsmtu00300 Lysine biosynthesisInhibitor     
Pathway (KEGG)

KEGG Glutamate metabolismKEGG Alanine and aspartate metabolismKEGG beta-Alanine metabolismKEGG Propanoate metabolismKEGG Butanoate metabolism

Gateway Clones

Comments

 
Rank: 3a Rv1293 LYSASwissProt: P0A5M4 P31848
Status: Crystal Structure   •   PDB: 1hkv  1hkw  [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 4 Rv3340 metCSwissProt: O53390 Q7D5N9
Status: [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

KEGG Methionine metabolism KEGG Cysteine metabolism KEGG Selenoamino acid metabolism KEGG Sulfur metabolism

Gateway Clones

Comments

 
Rank: 4a Rv3341 MetASwissProt: P0A5J8 O53391
Status: purified 06 [edit]
Analysis of PDB2B61TmH1
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 4b Rv0391 metZSwissProt: P95199 Q7D9W7
Status: Expressed [edit]
Analysis of PDB     TmH1
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 4c Rv2335 cysESwissProt: P95231
Status: [edit]
Analysis of PDB1S80, 1SSM, 1SSQ, 1SST, 1T3D, 1Y7LTmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 4d Rv0848 CysK2SwissProt: Q79FV4
Status: [edit]
Analysis of PDB1O58, 1VE1, 1Y7L, 1Z7W, 1Z7Y, 2BHS, 2BHTTmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 5 Rv2629 SwissProt: O06183 Q7D6V1
Status: [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 6 Rv0678 SwissProt: O53786 Q7D9F9
Status: [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 7 Rv2004c SwissProt: P0A5F9 Q10852
Status: [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 8 Rv0275c fadD27SwissProt: Q7DA42 Q79FZ1
Status: stopped [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 9 Rv2628 SwissProt: O06184 Q7D6V2
Status: expressed [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 10 Rv2830c SwissProt: P71622
Status: crystallized [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 11 Rv2626c SwissProt: O06186 Q7D6V4
Status: In PDB   •   PDB: N???[edit]
Analysis of PDB1XKF, 1Y5HTmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 12 Rv2035 SwissProt: O53479 Q7D7K9
Status: [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 13 Rv2497c pdhASwissProt: O06161 Q7D714
Status: [edit]
Analysis of PDBE. coli, human , 1L8A, 1NI4, 1RP7, 1W85, 1W88, 2G25, 2G28, 2PDD, 2PDETmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

BioCyc lactate oxidation BioCyc pyruvate dehydrogenase KEGG Glycolysis / Gluconeogenesis KEGG Alanine and aspartate metabolism KEGG Valine, leucine and isoleucine biosynthesis KEGG Butanoate metabolism

Gateway Clones

Comments

 
Rank: 13a Rv0843 pyruvate dehydrogenase E1 component alpha subunitSwissProt: O53855 Q7D966
Status: [edit]
Analysis of PDB1L8A, 1NI4, 1RP7, 1W85, 1W88, 2G25, 2G28, 2PDD, 2PDETmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 13b Rv2241 aceESwissProt: Q10504
Status: expressed [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 13c Rv2495c PdhCSwissProt: O06159
Status: Expressed [edit]
Analysis of PDB1B5S, 1DPB, 1DPC, 1DPD, 1EAA, 1EAB, 1EAC, 1EAD, 1EAE, 1EAF, 1FYC, 1IYU, 1IYV, 1LAB, 1LAC, 1W3D, 1W4E, 1W4F, 1W4G, 1W4H, 1W4I, 1W4J, 1W4K, 1W85, 1W88, 1Y8N, 1Y8O, 1Y8P, 2PDD, 2PDETmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 13d Rv0462 LpdSwissProt: P66004
Status:   •   PDB: 2A8X[edit]
Analysis of PDB1DXL, 1EBD, 1GJX, 1IVI, 1JEH, 1LPF, 1LVL, 1V59, 1ZMC, 1ZMD, 1ZY8, 2A8X, 2F5Z, 2PDD, 2PDE, 3LADTmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 13e Rv1820 IlvGSwissProt: P66946 Q50613
Status: [edit]
Analysis of PDB1T9A, 1T9B, 1T9C, 1T9D, 1YBH, 1YHY, 1YHZ, 1YI0, 1YI1, 1Z8N, 2F1F, 2FGCTmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 14 Rv2630 SwissProt: O06182 Q7D6V0
Status: [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 15 Rv2115c SwissProt: P63345 O33250
Status: cloned [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 16 Rv2623 SwissProt: O06189 Q7D6V7
Status: crystallized [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 17 Rv2627c SwissProt: O06185
Status: expressed [edit]
Analysis of PDB     TmH1
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 18 Rv3131 SwissProt: P95195
Status: soluble [edit]
Analysis of PDB     TmH1
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 19 Rv2032 acgSwissProt: O53476
Status: soluble [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 20 Rv2624c SwissProt: O06188 Q7D6V6
Status: expressed [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 21 Rv1813c SwissProt: P64889 Q50620
Status: expressed [edit]
Analysis of PDB     TmH1
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 22 Rv2711 ideRSwissProt: P0A672 O08190
Status:   •   PDB: 1FX7 / 1U8R[edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 23 Rv3126c SwissProt: O05799 Q7D630
Status: cloned [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 24 Rv3128c pseudogeneSwissProt: Q93S66
Status: cloned [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 25 Rv3049c SwissProt: O53294 Q7D679
Status: [edit]
Analysis of PDBStreptomyces, MethylococcusTmH1
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 26 Rv3130c SwissProt: P0A650 O07035
Status: cloned [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 27 Rv2496c pdhBSwissProt: O06160 Q7D715
Status: [edit]
Analysis of PDBE. coli, humanTmH1
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

BioCyc lactate oxidation BioCyc pyruvate dehydrogenase KEGG Glycolysis / Gluconeogenesis KEGG Alanine and aspartate metabolism KEGG Valine, leucine and isoleucine biosynthesis KEGG Butanoate metabolism

Gateway Clones

Comments

 
Rank: 28 Rv3841 bfrBSwissProt: P96237 Q7BS08 Q7D4R7
Status: crystallized [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 29 Rv0569 SwissProt: O53766
Status: crystallized [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 30 Rv1738 SwissProt: P64887 P71996
Status: purified [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 31 Rv1734c SwissProt: P71992
Status: expressed [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 32 Rv0190 SwissProt: O07434 Q7DAA9
Status: [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 33 Rv3614c SwissProt: O06269 Q7D573
Status: purified 06 [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 34 Rv3616c SwissProt: O06267
Status: expressed 06 [edit]
Analysis of PDB     TmH1
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 35 Rv2007c fdxASwissProt: P64122 Q10839
Status: [edit]
Analysis of PDBBacillus, Azotobacter,TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

BioCyc reductive acetyl coenzyme A pathway BioCyc sulfate assimilation III

Gateway Clones

Comments

 
Rank: 36 Rv2694c SwissProt: O07196
Status: [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 37 Rv1874 SwissProt: O07755
Status: [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 38 Rv2557 SwissProt: P65003 Q50741
Status: cloned [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 39 Rv0872c PE_PGRSSwissProt: Q79FV3
Status: [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 40 Rv0251c hspSwissProt: O53673 Q7DA60
Status: crystallized [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 41 Rv3674c nthSwissProt: P63540 O69642
Status: soluble [edit]
Analysis of PDBBacillus, E.coliTmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 42 Rv3287c rsbWSwissProt: Q7D5S1 Q798J8
Status: expressed [edit]
Analysis of PDBBacillus, Thermotoga,T4 ...TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 43 Rv1152 SwissProt: O06550 Q7D8R6
Status: selected [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 44 Rv2031c hspXSwissProt: P0A5B7 P30223
Status: purified [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 45 Rv2030c SwissProt: O53475 Q7D7L3
Status: [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 46 Rv3338 SwissProt: O53388
Status: [edit]
Analysis of PDB     TmH1
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 47 Rv2516c SwissProt: O53221 Q8VJH0
Status: [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 48 Rv0116c SwissProt: O53638
Status: purified [edit]
Analysis of PDB     TmH1
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

 
Rank: 49 Rv3916c SwissProt: O53594 Q7D4L8
Status: Expressed [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

Gateway Clones

Comments

It is one of the 7 genes susseptible to reactive nitrogen intermediates (RNI) in the macrophage.

 
Rank: 50 Rv0197 SwissProt: O53648
Status: [edit]
Analysis of PDB     TmH     
Metabolism Related Targets     Inhibitor     
Pathway (KEGG)

KEGG Nitrogen metabolism

Gateway Clones

Comments

 
Rank: 51 Rv3127 SwissProt: O05800