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Operon Browser for M. tuberculosis H37Rv (83332) • Randomly selected an operon

There are 764 total operons predicted by the MicrobesOnLine.org method for the H37Rv genome.
• The numbered grey boxes are 'segments' of the genome, each containing a visible set of operons to be displayed.
• The colored boxes below are operons. Mouse over to see some information and click them to view the operon page.

Name Rvmc16: 89,575 to 96,892  •  7 Members

More operon predictions in which 1 or more members has been predicted:
Rv0081Rvmc16MicrobesOnLine.org
Rv0081Rv_dir15The University of Maryland Center for Bioinformatics and Computational Biology
Rv0081Rv0081-Rv0088GenBank's internal operon classification
Rv0081nar_Rv0079-Rv0083A predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.
Rv0081OpMeth_Rv0080Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003;4(9):R59. 2003 Aug 29.

Rv0082Rvmc16MicrobesOnLine.org
Rv0082Rv_dir15The University of Maryland Center for Bioinformatics and Computational Biology
Rv0082Rv0081-Rv0088GenBank's internal operon classification
Rv0082nar_Rv0079-Rv0083A predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.
Rv0082OpMeth_Rv0080Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003;4(9):R59. 2003 Aug 29.

Rv0083Rvmc16MicrobesOnLine.org
Rv0083Rv_dir15The University of Maryland Center for Bioinformatics and Computational Biology
Rv0083Rv0081-Rv0088GenBank's internal operon classification
Rv0083nar_Rv0079-Rv0083A predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.
Rv0083OpMeth_Rv0080Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003;4(9):R59. 2003 Aug 29.

Rv0084Rvmc16MicrobesOnLine.org
Rv0084Rv_dir15The University of Maryland Center for Bioinformatics and Computational Biology
Rv0084kyoto11_drtODB (Operon DataBase), Shujiro Okuda, Kyoto
Rv0084Rv0081-Rv0088GenBank's internal operon classification
Rv0084nar_Rv0084-Rv0086A predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.
Rv0084OpMeth_Rv0080Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003;4(9):R59. 2003 Aug 29.

Rv0085Rvmc16MicrobesOnLine.org
Rv0085Rv_dir15The University of Maryland Center for Bioinformatics and Computational Biology
Rv0085kyoto11_drtODB (Operon DataBase), Shujiro Okuda, Kyoto
Rv0085Rv0081-Rv0088GenBank's internal operon classification
Rv0085nar_Rv0084-Rv0086A predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.
Rv0085OpMeth_Rv0080Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003;4(9):R59. 2003 Aug 29.

Rv0086Rvmc16MicrobesOnLine.org
Rv0086Rv_dir15The University of Maryland Center for Bioinformatics and Computational Biology
Rv0086Rv0081-Rv0088GenBank's internal operon classification
Rv0086nar_Rv0084-Rv0086A predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.
Rv0086OpMeth_Rv0080Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003;4(9):R59. 2003 Aug 29.

Rv0087Rvmc16MicrobesOnLine.org
Rv0087Rv_dir15The University of Maryland Center for Bioinformatics and Computational Biology
Rv0087Rv0081-Rv0088GenBank's internal operon classification
Rv0087OpMeth_Rv0080Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003;4(9):R59. 2003 Aug 29.



1
Rv0081: INVOLVED IN TRANSCRIPTIONAL MECHANISM.
Rv0081, (MTV030.25), len: 114 aa. Probabletranscriptional regulator, highly similar to others e.g.AL078610|SCH35_52|T36657 probable transcription regulatorfrom Streptomyces coelicolor (117 aa), FASTA scores: opt:404, E(): 4.8e-22, (58.2% identity in 110 aa overlap);AAG02351.1|AF210249_10|AF210249 metal-dependent regulatoryprotein from Streptomyces verticillus (113 aa);NP_435817.1|NC_003037 Putative transcriptional regulatorfrom Sinorhizobium meliloti (115 aa); etc.
experimental evidence, no additional detailsrecorded
External Links: 15607223O53626887012

2
Rv0082: UNKNOWN; PROBABLY INVOLVED IN CELLULARMETABOLISM.
Rv0082, (MTV030.26), len: 159 aa. Probableoxidoreductase (EC 1.-.-.-), highly highly similar orsimilar to other various oxidoreductases e.g.NP_143304.1|NC_000961 NADH-ubiquinone oxidoreductasesubunit from Pyrococcus horikoshii (173 aa);NP_126406.1|NC_000868 CO-induced hydrogenase related,subunit L from Pyrococcus abyssi (170 aa);HYCG_ECOLI|P16433 formate hydrogenlyase subunit 7 fromEscherichia coli (255 aa), FASTA scores: opt: 442, E():8e-29, (43.2% identity in 148 aa overlap); etc.
External Links: 15607224O53627886968

3
Rv0083: UNKNOWN; PROBABLY INVOLVED IN CELLULARMETABOLISM.
Rv0083, (MTV030.27, MTCY251.01), len: 640 aa.Probable oxidoreductase (EC 1.-.-.-), showing somesimilarity to other various oxidoreductases e.g.AAK06855.1|AF335723_1|AF335723 hydrogenase-4 component Bfrom Burkholderia pseudomallei (668 aa); HYFB_ECOLI|P23482 hydrogenase-4 component b from Escherichiacoli strain K12 (672 aa), FASTA scores: opt: 995, E(): 0,(32.2% identity in 571 aa overlap);AAF13041.1|AF157639_1|AF157639 putative formatehydrogenlyase integral membrane subunit fromDesulfitobacterium dehalogenans (637 aa); etc.
External Links: 15607225Q10880886965

4
Rv0084: INVOLVED IN HYDROGEN METABOLISM; FHL PATHWAY.
Rv0084, (MTCY251.02), len: 316 aa. Possible hycD(alternate gene name: hevD), formate hydrogenlyase (EC1.-.-.-), integral membrane protein, similar to otherse.g. HYCD_ECOLI|P16430 formate hydrogenlyase subunit 4from Escherichia coli (307 aa), FASTA scores: opt: 570,E(): 2.1e-26, (33.8% identity in 305 aa overlap);AAK06856.1|AF335723_2|AF335723 formate hydrogenlyasesubunit 4 from Burkholderia pseudomallei (316 aa);NP_457244.1|NC_003198 formate hydrogenlyase subunit 4 fromSalmonella enterica subsp. enterica serovar Typhi (307aa); etc. Also similar to NUOH_ECOLI|P33603 NADHdehydrogenase I chain H from Escherichia coli (325 aa),FASTA scores: opt: 207, E(): 9.5e-06, (26.5% identity in260 aa overlap). BELONGS TO THE COMPLEX I SUBUNIT 1FAMILY.; hevD
External Links: 15607226Q10881886959

5
Rv0085: INVOLVED IN HYDROGEN METABOLISM.
Rv0085, (MTCY251.03), len: 220 aa. Possible hycP,hydrogenase (EC 1.-.-.-), integral membrane protein,weakly similar to P77524|HYFE_ECOLI HYDROGENASE-4COMPONENT E from Escherichia coli (216 aa), FASTA scores:opt: 204, E():1.2e-07, (25.5% identity in 216 aaoverlap).
External Links: 15607227P64681886973

6
Rv0086: POSSIBLY INVOLVED IN HYDROGEN METABOLISM.
Rv0086, (MTCY251.04), len: 488 aa. Possible hycQ,hydrogenase (EC 1.-.-.-), integral membrane protein,weakly similar to P77437|HYFF_ECOLI HYDROGENASE-4COMPONENT F from Escherichia coli (526 aa), FASTA scores:opt: 948, E(): 0, (35.9% identity in 493 aa overlap); andAAK06855.1|AF335723_1|AF335723 hydrogenase-4 component Bfrom Burkholderia pseudomallei (668 aa). Also similar tod9087711 & NUOL_ECOLI|P33607 NADH dehydrogenase I chain Lfrom Escherichia coli (613 aa), FASTA scores: opt: 360,E():3.2e-13, (27.9% identity in 488 aa overlap); and toNUON_ECOLI|P33608 NADH dehydrogenase I chain N fromEscherichia coli (425 aa), FASTA scores: opt: 375, E():3.9e-14, (25.0% identity in 432 aa overlap).
External Links: 15607228Q10883886963

7
Rv0087: INVOLVED IN HYDROGEN METABOLISM; FHL PATHWAY.
Rv0087, (MTCY251.05), len: 492 aa. Possible hycE(alternate gene name: hevE), formate hydrogenlyase (EC1.-.-.-), similar to others e.g. HYCE_ECOLI|P16431 formatehydrogenlyase subunit 5 from Escherichia coli (569 aa),FASTA scores: opt: 680, E(): 1.8e-38, (31.2% identity in449 aa overlap); NP_457243.1|NC_003198 formatehydrogenlyase subunit 5 from Salmonella enterica subsp.enterica serovar Typhi (569 aa); NP_275541.1|NC_000916formate hydrogenlyase subunit 5 from Methanothermobacterthermautotrophicus (370 aa); etc. Also some similaritywith NUOD_ECOLI|P33600 NADH dehydrogenase I chain D fromEscherichia coli (407 aa), FASTA scores: opt: 245, E():8.9e-10, (24.5% identity in 368 aa overlap). BELONGS TOTHE COMPLEX I 49 kDa SUBUNIT FAMILY.; hevE
External Links: 15607229Q10884886956