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Operon Browser for M. tuberculosis H37Rv (83332) • Randomly selected an operon

There are 764 total operons predicted by the MicrobesOnLine.org method for the H37Rv genome.
• The numbered grey boxes are 'segments' of the genome, each containing a visible set of operons to be displayed.
• The colored boxes below are operons. Mouse over to see some information and click them to view the operon page.

Name Rvmc437: 2,506,278 to 2,508,452  •  3 Members

More operon predictions in which 1 or more members has been predicted:
Rv2232Rvmc437MicrobesOnLine.org
Rv2232Rv_dir512The University of Maryland Center for Bioinformatics and Computational Biology
Rv2232Rv2228c-cobCGenBank's internal operon classification
Rv2232nar_Rv2230c-Rv2231cA predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.
Rv2232OpMeth_Rv2229cInference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003;4(9):R59. 2003 Aug 29.

Rv2234Rvmc437MicrobesOnLine.org
Rv2234Rv_dir512The University of Maryland Center for Bioinformatics and Computational Biology
Rv2234kyoto423_drtODB (Operon DataBase), Shujiro Okuda, Kyoto
Rv2234Rv2228c-cobCGenBank's internal operon classification
Rv2234nar_Rv2230c-Rv2231cA predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.
Rv2234OpMeth_Rv2229cInference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003;4(9):R59. 2003 Aug 29.

Rv2235Rvmc437MicrobesOnLine.org
Rv2235Rv_dir512The University of Maryland Center for Bioinformatics and Computational Biology
Rv2235Rv2232-Rv2235GenBank's internal operon classification



1
Rv2232: UNKNOWN
Rv2232, (MTCY427.13), len: 291 aa. Conservedhypothetical protein, similar to members of haloaciddehalogenase-like family from several bacteria and toputative phosphatases e.g. Q9I767 and AAK78398. ContainsN-terminal extension. FASTA scores: Q9I767 HYPOTHETICALPROTEIN PA0065 (221 aa) opt: 439 E(): 3.2e-18; 38.679%identity (40.196% ungapped) in 212 aa overlap;>>tr|AAK78398 Predicted phosphatase, HAD family (216 aa)opt: 427, E(): 1.5e-17; 34.762% identity (35.437%ungapped) in 210 aa overlap. Replaces previous Rv2232 andRv2233.
External Links: 57116958P68911Q10515887597

2
Rv2234: INVOLVED IN SIGNAL TRANSDUCTION (VIADEPHOSPHORYLATION). CAN DEPHOSPHORYLATED IN VITRO THEPHOSPHOTYROSINE RESIDUE OF MYELIN BASIC PROTEIN (MBP) ATpH 7.0 [CATALYTIC ACTIVITY: Protein tyrosine phosphate +H(2)O = protein tyrosine + phosphate].
Rv2234, (MTCY427.15), len: 163 aa. ptpA (alternategene name: MPtpA), low molecular weightprotein-tyrosine-phosphatase (see citations below) (EC3.1.3.48), similar to other phosphotyrosine proteinphosphatases e.g. P53433|PTPA_STRCO LOW MOLECULAR WEIGHTPROTEIN-TYROSINE PHOSPHATASE from Streptomyces coelicolor(164 aa), FASTA scores: opt: 455, E(): 3.3e -25, (49.7%identity in 155 aa overlap); PA1S_HUMAN|P24667 red cellacid phosphatase 1, FASTA score: (37.7% identity in 138 aaoverlap); etc. Contains a phosphatase catalytic sitedomain located in N-terminal part. Activity provenbiochemically. Supposed a secreted protein.; MPtpA
experimental evidence, no additional detailsrecorded
External Links: 15609371P65716P65716887373

3
Rv2235: UNKNOWN: MAY BE INVOLVED IN THE ABILITY TOSURVIVE IN MACROPHAGES.
Rv2235, (MTCY427.16), len: 271 aa. Probableconserved transmembrane protein (see Miller & Shinnick2001); hydrophobic regions near N- and C-terminus. Similarto conserved membrane proteins in other Actinomycetes.Equivalent to Mycobacterium leprae. ML1644 (270 aa). FASTAscores: opt: 1357, E(): 1.2e-72; 74.170% identity in 271aa overlap T44717|3150235|CAA19213.1|AL02363513093419|CAC30595.1|AL583922.
experimental evidence, no additional detailsrecorded
External Links: 15609372P66883P66883887606