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Operon Browser for M. tuberculosis H37Rv (83332) • Randomly selected an operon

There are 764 total operons predicted by the MicrobesOnLine.org method for the H37Rv genome.
• The numbered grey boxes are 'segments' of the genome, each containing a visible set of operons to be displayed.
• The colored boxes below are operons. Mouse over to see some information and click them to view the operon page.

Name Rvmc280: 1,552,654 to 1,561,269  •  7 Members

More operon predictions in which 1 or more members has been predicted:
Rv1379Rvmc280MicrobesOnLine.org
Rv1379Rv_dir331The University of Maryland Center for Bioinformatics and Computational Biology
Rv1379kyoto264_drtODB (Operon DataBase), Shujiro Okuda, Kyoto
Rv1379pyrR-pyrFGenBank's internal operon classification

Rv1380Rvmc280MicrobesOnLine.org
Rv1380Rv_dir331The University of Maryland Center for Bioinformatics and Computational Biology
Rv1380kyoto264_drtODB (Operon DataBase), Shujiro Okuda, Kyoto
Rv1380pyrR-pyrFGenBank's internal operon classification
Rv1380nar_Rv1380-Rv1383A predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.
Rv1380OpMeth_Rv1380Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003;4(9):R59. 2003 Aug 29.

Rv1381Rvmc280MicrobesOnLine.org
Rv1381Rv_dir331The University of Maryland Center for Bioinformatics and Computational Biology
Rv1381kyoto264_drtODB (Operon DataBase), Shujiro Okuda, Kyoto
Rv1381pyrR-pyrFGenBank's internal operon classification
Rv1381nar_Rv1380-Rv1383A predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.
Rv1381OpMeth_Rv1380Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003;4(9):R59. 2003 Aug 29.

Rv1382Rvmc280MicrobesOnLine.org
Rv1382Rv_dir331The University of Maryland Center for Bioinformatics and Computational Biology
Rv1382pyrR-pyrFGenBank's internal operon classification
Rv1382nar_Rv1380-Rv1383A predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.
Rv1382OpMeth_Rv1380Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003;4(9):R59. 2003 Aug 29.

Rv1383Rvmc280MicrobesOnLine.org
Rv1383Rv_dir331The University of Maryland Center for Bioinformatics and Computational Biology
Rv1383pyrR-pyrFGenBank's internal operon classification
Rv1383nar_Rv1380-Rv1383A predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.
Rv1383OpMeth_Rv1380Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003;4(9):R59. 2003 Aug 29.

Rv1384Rvmc280MicrobesOnLine.org
Rv1384Rv_dir331The University of Maryland Center for Bioinformatics and Computational Biology
Rv1384pyrR-pyrFGenBank's internal operon classification
Rv1384nar_Rv1384-Rv1385A predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.

Rv1385Rvmc280MicrobesOnLine.org
Rv1385Rv_dir331The University of Maryland Center for Bioinformatics and Computational Biology
Rv1385pyrR-pyrFGenBank's internal operon classification
Rv1385nar_Rv1384-Rv1385A predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.
Rv1385OpMeth_Rv1380Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003;4(9):R59. 2003 Aug 29.



1
Rv1379: BINDS TO THE CONSERVED SEQUENCE IN THE PYROPERON MRNA AND DISRUPTS THE ANTITERMINATOR, PERMITTINGTERMINATOR HAIRPIN FORMATION AND PROMOTING TRANSCRIPTIONTERMINATION
regulates pyrimidine biosynthesis by binding to themRNA of the pyr genes, also has been shown to have uracilphosphoribosyltransferase activity
External Links: 15608519P65941886769

2
Rv1380: INVOLVED IN PYRIMIDINE BIOSYNTHESIS (SECONDSTEP) [CATALYTIC ACTIVITY : CARBAMOYL PHOSPHATE +L-ASPARTATE = PHOSPHATE + N-CARBAMOYL-L-ASPARTATE]
catalyzes the transfer of the carbamoyl moiety fromcarbamoyl phosphate to L- aspartate in pyrimidinebiosynthesis
External Links: 15608520P65613886771

3
Rv1381: INVOLVED IN PYRIMIDINE BIOSYNTHESIS (THIRDSTEP) [CATALYTIC ACTIVITY: (S)-DIHYDROOROTATE + H(2)O =N-CARBAMOYL-L-ASPARTATE]
catalyzes the formation of N-carbamoyl-L-aspartatefrom (S)-dihydroorotate in pyrimidine biosynthesis
External Links: 15608521P71809886765

4
Rv1382: UNKNOWN
Rv1382, (MTCY02B12.16), len: 165 aa. Possibleexported or membrane protein, hydrophobic domain atN-terminus.
External Links: 15608522P71810886767

5
Rv1383: INVOLVED IN BOTH ARGININE AND PYRIMIDINEBIOSYNTHESIS [CATALYTIC ACTIVITY : 2 ATP + L-GLUTAMINE +CO(2) + H(2)O = 2 ADP + PHOSPHATE + GLUTAMATE + CARBAMOYLPHOSPHATE]
catalyzes production of carbamoyl phosphate frombicarbonate and glutamine in pyrimidine and argininebiosynthesis pathways; forms an octamer composed of fourCarAB dimers
External Links: 15608523P71811886761

6
Rv1384: INVOLVED IN BOTH ARGININE AND PYRIMIDINEBIOSYNTHESIS [CATALYTIC ACTIVITY : 2 ATP + L-GLUTAMINE +CO(2) + H(2)O = 2 ADP + PHOSPHATE + GLUTAMATE + CARBAMOYLPHOSPHATE.]
four CarB-CarA dimers form the carbamoyl phosphatesynthetase holoenzyme that catalyzes the production ofcarbamoyl phosphate; CarB is responsible for theamidotransferase activity
External Links: 57116856P57689886253

7
Rv1385: INVOLVED IN THE BIOSYNTHESIS OF PYRIMIDINES[CATALYTIC ACTIVITY : OROTIDINE 5'-PHOSPHATE = UMP +CO(2)]
OMP decarboxylase; OMPDCase; OMPdecase; type 2subfamily; involved in last step of pyrimidinebiosynthesis; converts orotidine 5'-phosphate to UMP andcarbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
External Links: 15608524P0A5M6886763