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Operon Browser for M. tuberculosis H37Rv (83332) • Randomly selected an operon

There are 911 total operons predicted by the The University of Maryland Center for Bioinformatics and Computational Biology method for the H37Rv genome.
• The numbered grey boxes are 'segments' of the genome, each containing a visible set of operons to be displayed.
• The colored boxes below are operons. Mouse over to see some information and click them to view the operon page.

Name Rv_dir173: 865,851 to 869,763  •  3 Members

More operon predictions in which 1 or more members has been predicted:
Rv0773cRv_dir173The University of Maryland Center for Bioinformatics and Computational Biology
Rv0773cRv_dir175The University of Maryland Center for Bioinformatics and Computational Biology
Rv0773cggtA-Rv0774cGenBank's internal operon classification
Rv0773cnar_Rv0773c-Rv0774cA predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.

Rv0774cRv_dir173The University of Maryland Center for Bioinformatics and Computational Biology
Rv0774cRv_dir175The University of Maryland Center for Bioinformatics and Computational Biology
Rv0774cggtA-Rv0774cGenBank's internal operon classification
Rv0774cnar_Rv0773c-Rv0774cA predicted operon map for Mycobacterium tuberculosis. Nucleic Acids Res. 2007;35(15):5085-95. 2007 Jul 25.

Rv0776cRv_dir173The University of Maryland Center for Bioinformatics and Computational Biology
Rv0776cRv_dir175The University of Maryland Center for Bioinformatics and Computational Biology
Rv0776ckyoto140_drtODB (Operon DataBase), Shujiro Okuda, Kyoto



1
Rv0773c: BESIDES THE CEPHALOSPORIN ACYLASE I ACTIVITYWHICH CONVERTS GL-7ACA INTO 7-ACA; THIS ENZYME DISPLAYSSOME GAMMA GLUTAMYLTRANSPEPTIDASE ACTIVITY: GGT PLAYS AKEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THESYNTHESIS AND DEGRADATION OF GLUTATHIONE. [CATALYTICACTIVITY 1: 7-BETA-(4-CARBOXYBUTANAMIDO)-CEPHALOSPORANICACID + H2O = 7-AMINOCEPHALOSPORANIC ACID + GLUTARIC ACID][CATALYTIC ACTIVITY 2: (5-L-glutamyl)-peptide + an aminoacid = peptide + 5-L-glutamyl-amino acid].
Rv0773c, (MTCY369.18), len: 512 aa. Probable ggtA,bifunctional acylase including cephalosporin acylase (EC3.5.1.-), and gamma-glutamyl transpeptidase (EC 2.3.2.2);highly similar to others e.g. NP_295247.1|NC_001263cephalosporin acylase from Deinococcus radiodurans (535aa); NP_248854.1|NC_002516 probablegamma-glutamyltranspeptidase from Pseudomonas aeruginosa(538 aa); P15557|PAC1_PSES3 ACYLASE ACY 1 [INCLUDES:CEPHALOSPORIN ACYLASE (GL-7ACA ACYLASE);GAMMA-GLUTAMYLTRANSPEPTIDASE (GGT)] from Pseudomonas sp.strain SE83 (558 aa), FASTA scores: opt: 784, E(): 0,(34.2% identity in 526 aa overlap);NP_391491.1|NC_000964|Z93767|BSZ93767_6|O0521 proteinsimilar to gamma-glutamyltransferase from Bacillussubtilis (525 aa), FASTA scores: opt: 1169, E(): 0, (40.1%identity in 516 aa overlap); etc. Also similar toRv2394|ggtB from Mycobacterium tuberculosis. Member ofGL-7ACA ACYLASES AND TO GGT group.
External Links: 15607913P71828888893

2
Rv0774c: UNKNOWN; COULD HAVE POSSIBLY A LIPOLYTICACTIVITY.
Rv0774c, (MTCY369.19c), len: 303 aa. Possibleconserved exported protein with hydrophobic region nearN-terminus, highly similar, except in N-terminus, toRv0519c|Z97831|MTY20G10.09c|O33364 HYPOTHETICAL PROTEINfrom Mycobacterium tuberculosis (300 aa), FASTA scores:opt: 1092, E(): 0, (57.9% identity in 299 aa overlap).Contains PS00061 Short-chain alcohol dehydrogenase familysignature, and PS00120 Lipases, serine active site. Socould be a lipase (EC 3.1.-.-). Start changed since firstsubmission (-9 aa).
External Links: 57116780P71829888895

3
Rv0776c: UNKNOWN
Rv0776c, (MTCY369.21a), len: 259 aa. Conservedhypothetical protein, similar (except first 50 aa) toP72737|D90900_57 hypothetical protein from Synechocystissp. strain PCC 6803 (261 aa), FASTA scores: opt: 337, E():1.7e-15, (30.5% identity in 266 aa overlap).
External Links: 15607916P71831888918