| Structure Summary pages | This page is a front page portal to the structure information on known TB proteins. All other WebTB servers can be accessed from this page, including the Gallery and JMOL viewer. |
|---|
| MTBreg Database | A database of proteins up- and down-regulated in Mycobacterium tuberculosis grown under conditions mimicking infection as well as information on proteins that are regulated by selected transcription factors or other regulatory proteins. |
|---|
| ProLinks | The Prolinks database is a collection of inference methods used to predict functional linkages between proteins. These methods include the Phylogenetic Profile method, the Gene Cluster method, Rosetta Stone, and the Gene Neighbor method. |
|---|
| BLAST the TB genome | BLAST a sequence against the TB genome and other NCBI databases. |
|---|
| Mycobacterial Genome DataBase | The site is a database of genomes of mycobacterial strains sequenced in the lab of James C. Sacchettini at Texas A&M University. It provides access to sequence data (including coverage statistics) and comparison of polymorphisms among various strains of tuberculosis, with a focus on drug-resistance. The sequencing is done on an Illumina GenomeAnalyzer II (short reads). The data was analyzed using customized sequence-assembly methods written by Tom Ioerger and his group at Texas A&M. |
|---|
| Gene expression correlation display | This server presents the pairwise gene expression correlation for two or more genes. For a set of genes you can get all the pairwise correlations and express it as a matrix, graphically display it. |
|---|
| Operon Search | Search for operons and directons in the TB genome. Known operons are listed by name. These data will be expanded as more sources are found. |
|---|
| Top 100 Persistence Targets for the TB Structural Genomics Consortium | This is a page containing the Top 100 persistence targets. It is designed to allow anyone in the community to share any information they may know about a given target with the rest of the community. Please feel free to add your comments. |
|---|
| Target Explorer | Target Explorer is intended to be an interactive web site that allows researchers in the Tuberculosis research community to experiment with different target selection criteria and explore alternative ways of prioritizing gene targets for experimentation (crystallization structure solution, high-throughput screening for inhibitor discovery, etc.) |
|---|
| The Genome browser | Graphically scan the entire TB genome for information on each ORF with indications of any predicted operons and includes links back to the quick search page for more gene information |
|---|
| ORF Progress search tool | Search the status and progress of MTb ORFs that are targeted and pursued by consortium members. |
|---|
| Structure Gallery | See the protein structures determined by members of the consortium. |
|---|
| Knockout and Cosmid Libraries | From the TB research group of Bill Jacob's at AECOM. |
|---|
| TBDB Legacy Tools | Legacy tools from the former TBSGC site to search and browse the TB Genome |
|---|